
Pollution has a detrimental impact on the health of people worldwide, causing premature deaths and a range of health issues. Air pollution, in particular, is a familiar environmental health hazard, with nine out of ten people breathing polluted air, leading to 7 million premature deaths annually. The effects of air pollution are felt by all, but certain vulnerable groups, such as children, the elderly, and those with pre-existing health conditions, are more severely affected. Studies have linked air pollution to respiratory infections, heart disease, stroke, lung cancer, and other serious illnesses. Additionally, indoor air pollution from open fires, stoves, and candles can also have harmful consequences. Water and land pollution further contribute to the overall impact of pollution on human health and the environment. As pollution undermines sustainable economic growth and exacerbates inequality, it is crucial to address its root causes and implement interventions to improve air quality and protect public health.
| Characteristics | Values |
|---|---|
| Global pollution is rising due to | rapid economic growth, population increases, and insufficient environmental management |
| Pollutants | Air pollution, water pollution, hazardous chemicals, and wastes like mercury, lead, and persistent organic pollutants (POPs) |
| Effects of pollutants | Debilitating and fatal illnesses, harmful living conditions, destruction of ecosystems, and long-term environmental damage |
| Most vulnerable groups | Children, elderly people, people with chronic health issues, people with asthma, people with cardiovascular or respiratory disease, and people from low-income communities |
| Diseases caused by pollution | Cancer, cardiovascular disease, respiratory diseases, diabetes mellitus, obesity, reproductive disorders, neurological disorders, immune system disorders, neurodevelopmental and metabolic diseases in children |
| Mortality rates | Air pollution causes 7 million premature deaths each year, with more than 90% of deaths occurring in low- and middle-income countries |
| Indoor pollution | Indoor air can be more polluted than outdoor air, with pollutant concentrations two to five times higher; common indoor air pollutants include radon, smoke, lead dust, carbon monoxide, mold, and volatile organic compounds |
| Interventions | Reducing air pollution, addressing linkages between pollution, health, climate change, and fiscal solutions, promoting a circular economy, sustainable chemistry, resource efficiency, and sustainable markets |
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What You'll Learn

Air pollution and respiratory health
Air pollution is a familiar environmental health hazard. The air we breathe is necessary for survival, and it is impacted by pollution every day. The sources of air pollution are diverse and can be categorised into household air pollution (HAP) and ambient air pollution (AAP). About 93% of children are exposed to ambient levels of PM2.5 above WHO guideline limits. AAP was responsible for 4.2 million premature deaths in 2016, of which almost 286,000 were children under the age of five.
AAP affects childhood acute respiratory infections, asthma, pneumonia, lung function, hypertension, and even cancers. Globally, pneumonia is the leading infectious disease of paediatric mortality, especially among children under the age of five. In 2019, pneumonia accounted for 14% of deaths among children under the age of five and 22% of deaths among children aged 1-5. Studies have shown that living near highways and breathing in vehicle pollution increases the risk of developing breast cancer. Exposure to airborne chemicals used in aerosol products and paint removers has also been shown to increase breast cancer rates. Lung cancer rates in industrialised areas also show the effects of pollution on human health. The burning of coal creates heavily polluted air, increasing lung cancer rates in communities where coal is used to generate energy.
Daily exposure to nitrogen oxides (chemical compounds found in car exhaust and smog) has been shown to increase a person's risk of stroke. These same chemicals can also decrease the amount of good cholesterol in our bodies, increasing the odds of developing other cardiovascular diseases. Air pollutants are thought to compromise a child's immune system against pathogens in the respiratory tract. Exposure to air pollutants can compromise the inflammatory mechanism and render one more susceptible to developing acute lower respiratory infections.
Studies have linked particle pollution exposure to a variety of respiratory health effects, including respiratory symptoms such as cough, phlegm, and wheezing; acute, reversible decrements in pulmonary function; inflammation of the airways and lungs; bronchial hyperreactivity; acute phase reactions; respiratory infections; respiratory emergency department visits; respiratory hospitalizations; decreased lung function growth in children; chronic loss of pulmonary function in adults; asthma development; and premature mortality in people with chronic lung disease.
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Pollution and cancer
Air pollution is a familiar environmental health hazard, and its effects on human health are far-reaching. According to the World Health Organization (WHO), 99% of the world's population breathes unhealthy air. The health risks associated with air pollution are comparable to those caused by smoking tobacco.
One of the most prevalent health issues caused by exposure to air pollution is cancer. Studies have shown a link between air pollution and lung cancer, with nearly half of lung cancer cases in people who have never smoked estimated to be related to air pollution. The mining and burning of coal, for example, create heavily polluted air, increasing lung cancer rates in communities where coal is used. Furthermore, living near highways and breathing in vehicle pollution increases the risk of developing breast cancer. Exposure to airborne chemicals in aerosol products and paint removers also increases breast cancer rates.
Particulate matter, known as PM2.5, is a significant contributor to air pollution and has been linked to an increased risk of mortality from various cancers, including lung, breast, liver, and pancreatic cancer. The specific mechanisms by which PM2.5 exposure may lead to cancer are still being studied, but researchers have identified a few potential explanations. Pollution may cause defects in DNA repair functions, alterations in the body's immune response, or inflammation that triggers angiogenesis, facilitating tumour growth and spread. Additionally, in the case of the digestive organs, pollution could affect gut microbiota and influence the development of cancer.
While pollution is a risk factor for cancer, other factors such as diet and exercise may be more significant and modifiable. Nevertheless, reducing air pollution directly mitigates the risk of developing lung cancer and has additional health benefits. Increasing green spaces, adopting cleaner energy sources, and promoting active transportation (walking and cycling) can lead to a healthier lifestyle, increased physical activity, and lower rates of other non-communicable diseases, thereby reducing the likelihood of developing certain cancers.
Overall, air pollution poses a serious threat to public health, and its link to cancer underscores the importance of implementing measures to improve air quality and reduce pollution levels.
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Mental health and pollution
Air pollution is a significant environmental health risk and is the single biggest environmental threat to human health, according to the World Health Organization (WHO). The links between air pollution and health conditions such as respiratory and cardiovascular diseases are well-established. However, the impact of air pollution on mental health is less well-understood, although there is substantial evidence of a connection.
Research has associated air pollution with higher levels of stress, psychological distress, and an increased risk of dementia, Alzheimer's, and depression. A large study of people in the US and Denmark found a link between exposure to air pollution and an increased risk of psychiatric disorders, including depression, schizophrenia, bipolar disorder, and personality disorder. Another study found that even a small, short-term increase in PM2.5 (fine particulate matter) of 10 micrograms per cubic meter was associated with a significant increase in children presenting at hospitals with severe psychiatric symptoms.
The exact mechanisms by which air pollution affects mental health are still being investigated. However, one theory suggests that it is related to neuroinflammatory responses in the brain. Air pollution may also exacerbate existing mental health conditions, especially in children. Additionally, indoor air pollution can also impact mental health, and building air quality improvement programs can help mitigate this issue.
Water pollution, particularly in low-income areas, also contributes to mental health deterioration. Studies have found that pollutants such as lead, arsenic, mercury, and cadmium are significantly associated with negative mental health outcomes. Furthermore, extreme weather events caused by climate change, such as floods, hurricanes, wildfires, and droughts, can lead to mental health issues, especially in vulnerable groups, including females, children, minorities, and people with low socioeconomic status.
Noise pollution is another factor that can negatively affect mental health. It has been shown to induce the pituitary-adrenal-cortical axis and the sympathetic-adrenal-medullary axis, which can impact overall well-being and mental health.
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Pollutants in water
Water is the second most vital element for life on Earth, after the air we breathe. However, due to human interference, the small portion of water available for drinking is becoming increasingly contaminated. Water pollution has far-reaching consequences for human life and severely impacts human health.
Water pollution can cause reproductive problems in both men and women. In men, continuous intake of polluted water contaminated with toxic substances can lead to erectile dysfunction and low sperm count. In severe cases, prolonged consumption can result in azoospermia, the absence of motile sperm production. For pregnant women, consuming contaminated water can result in their offspring developing neurological issues or congenital disabilities such as cleft mouth or neonatal meningitis.
Water pollution also poses a serious threat to children's health. Diarrhoea, a common symptom of gastrointestinal diseases, can indicate a more serious chronic disease such as typhoid, cholera, or dysentery. These diseases are caused by contaminated water sources and the consumption of vegetables irrigated with polluted water.
In addition to its direct impact on human health, water pollution significantly affects the environment. Pollutants harm aquatic life, leading to biodiversity loss and habitat destruction. Excess nutrients cause oxygen-depleting algal blooms, creating dead zones. Water pollution also impacts food safety, as toxins accumulate in crops and livestock, and can cause recreational hazards, with swimmers facing infections and illnesses.
Water pollution is a pressing issue that requires attention at both the domestic and municipal levels. Preventive measures, such as the use of water purifiers and the implementation of proper wastewater treatment plants, are crucial to mitigating the deteriorating health effects of water pollution.
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Indoor air pollution
The health effects of indoor air pollution are extensive. Short and long-term exposure can lead to respiratory diseases, heart disease, cognitive deficits, and even cancer. Poor indoor air quality has been linked to an increased risk of developing pneumonia during childhood, with prenatal exposure potentially impairing lung function in infants. Furthermore, indoor air pollution during pregnancy has been associated with an increased risk of postpartum depression.
Worldwide, around 2.1 billion people rely on solid fuels like wood, charcoal, and coal for cooking, contributing to harmful household air pollution. This lack of access to clean fuels and technologies is a critical issue, particularly in sub-Saharan Africa, where population growth has outpaced the availability of clean cooking alternatives. The combined effects of ambient and household air pollution are associated with approximately 6.7 million premature deaths annually, with an estimated 3.2 million deaths attributed solely to household air pollution in 2020.
Improving indoor air quality requires a range of interventions, including the adoption of clean-burning technologies, improved ventilation, and policy actions to support access to cleaner fuels and technologies. These measures are crucial to reducing the health burden of indoor air pollution, especially for vulnerable populations who are disproportionately affected.
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Frequently asked questions
Pollution affects the health of the population in a variety of ways. Air pollution, for example, has been linked to an increased risk of respiratory infections, heart disease, stroke, lung cancer, and other cardiovascular diseases. It can also trigger asthma attacks and acute bronchitis, and may increase the risk of respiratory infections, especially in children.
Vulnerable populations include the very young, older adults, and people with pre-existing health conditions such as cardiovascular or respiratory disease. These groups tend to spend more time indoors, where the concentration of some pollutants can be two to five times higher than outdoors.
Outdoor air pollution is the leading environmental risk to health, causing around 7 million premature deaths each year. It is also the main cause of disability-adjusted life years lost (DALYs) in Europe.
Exposure to air pollution during and after pregnancy increases the risk of postpartum depression. Exposure to wildfire smoke during pregnancy has also been linked to an increased risk of preterm birth.










































