
Drugs and pollutants can affect fertility in both men and women. In women, fertility is especially susceptible to disruption, as many factors and systems must work together for conception to occur. In men, fertility is often related to sperm production.
Drugs
Illicit drugs such as cocaine, crystal meth, opioids, and cannabis can cause adverse effects at most levels of the reproductive system and cause a high rate of miscarriages. They can also lead to risky sexual behaviour, which can cause unwanted pregnancies and sexually transmitted infections that can result in infertility.
Prescription drugs can also affect fertility. For example, thyroid medications and medications for mental health disorders can impact fertility in women.
Pollution
Pollutants such as endocrine disruptors found in pesticides, plastics, and air pollution can interfere with hormonal balance, disrupt ovulation, and impair sperm quality.
Lifestyle
Lifestyle choices such as diet, exercise, smoking, and alcohol consumption can also influence reproductive health. For example, obesity is linked to lower sperm count and quality in men, and strenuous physical labour and taking multiple medications are known to reduce sperm count.
Characteristics | Values |
---|---|
--- | --- |
Endocrine disruption | Loss of blood-sugar control |
Damage to the female reproductive system | Anovulation, impaired implantation, and loss of fetal viability |
Damage to the male reproductive system | Reduced sperm count and function |
Impaired fetal viability | Miscarriage, stillbirth, neonatal death, and congenital defects |
What You'll Learn
- Tobacco, alcohol, and drug addiction are major causes of infertility in both men and women
- Tobacco use can delay pregnancy by over a year and cuts the chances of conceiving by more than half
- Cannabis disrupts the menstrual cycle and decreases ovulation
- Opioids disrupt pituitary and hypothalamus hormone production, causing menstrual irregularities and halting ovulation
- Cocaine and ecstasy use can lead to permanent reproductive problems for people of all genders
Tobacco, alcohol, and drug addiction are major causes of infertility in both men and women
Tobacco
Smoking is known to affect fertility in both men and women. Women who smoke are twice as likely to be infertile as non-smokers, and smoking can also reduce the success rates of fertility treatments such as IVF. In men, smoking affects fertility by reducing sperm count and quality and increasing the risk of impotence. Quitting smoking can improve fertility outcomes, and women who stop smoking do not take any longer to get pregnant than those who have never smoked.
Alcohol
Alcohol consumption can also negatively impact fertility in both men and women. In men, heavy drinking is linked to reduced sperm count and quality, decreased libido, and sexual dysfunction. In women, alcohol can affect hormones and ovulation, making it harder to conceive and increasing the time it takes to get pregnant. Health authorities warn that drinking alcohol during pregnancy can harm the baby and increase the risk of miscarriage, stillbirth, and other complications.
Drugs
Recreational drug use can reduce the chance of pregnancy and increase the risk of reproductive problems and infertility in both men and women. For example, cannabis use can lower men's sperm count and affect women's hormones, reducing the chance of pregnancy. Long-term use of drugs such as cocaine, heroin, and ecstasy can lead to permanent reproductive problems for people of all genders. Anabolic steroids used for bodybuilding or sports can cause testes to shrink and stop sperm production, and it can take years for sperm levels to return to normal after stopping steroid use.
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Tobacco use can delay pregnancy by over a year and cuts the chances of conceiving by more than half
Tobacco use is a major cause of infertility in both men and women. It directly affects fertility by acting on the body systems responsible for reproduction, and it also has an indirect effect due to how tobacco use and addiction can affect health and lifestyle. Tobacco use can also have negative effects on the pregnancy and the baby. These negative effects are most likely to happen during the first three months of the pregnancy when the woman might not even realise she is pregnant. Tobacco use can cause serious complications during pregnancy, including premature labour and birth, and it also increases the risk of sudden infant death syndrome (SIDS).
Women who smoke take longer to get pregnant than non-smokers. The more a woman smokes, the longer it may take her to get pregnant. Even low levels of smoking (between 5 and 9 cigarettes a day) can make it more difficult to conceive. Women who smoke are twice as likely to be infertile as non-smokers, and this is true for women trying to become pregnant for the first time or who have been pregnant before. Tobacco use can also affect the success rates of fertility treatments such as IVF. Secondhand smoke can also reduce the chance of getting pregnant.
Women who smoke have been shown to take over a year longer, on average, to conceive than non-smokers, and their chances of conceiving are cut by more than half. Tobacco thickens cervical mucus and blocks sperm from reaching the egg.
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Cannabis disrupts the menstrual cycle and decreases ovulation
Cannabis is the most commonly used illicit drug in the United States and its use is increasing. Studies have shown that THC, the main active compound in cannabis, can affect the menstrual cycle and decrease ovulation.
THC has been shown to block ovulation in many mammals, including primates, by suppressing the production of luteinizing hormone, a hormone critical to the ovulation process. THC may also inhibit the production of other hormones, such as prolactin and cortisol, and decrease sex drive, further reducing the chances of conception.
Regular smokers may have an elevated risk of not ovulating at all, and some studies suggest that marijuana disrupts the menstrual cycle and can lead to anovulatory cycles (cycles without ovulation).
In addition, marijuana use may increase the likelihood of infertility and miscarriage in women. Marijuana crosses the placenta and may affect the fetus, although specific studies on the precise impact on the baby are not readily available.
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Opioids disrupt pituitary and hypothalamus hormone production, causing menstrual irregularities and halting ovulation
Opioids are a class of drugs that are used to relieve pain. They are highly addictive and can be prescribed by doctors or obtained illegally. They can have a negative impact on fertility in both men and women.
In women, opioids can disrupt the production of hormones by the pituitary and hypothalamus, which can cause menstrual irregularities and stop ovulation. This is because opioids can affect the hypothalamic-pituitary-gonadal axis, which is responsible for the production of sex hormones. This can lead to a decrease in testosterone and oestradiol, which can cause a reduction in libido and erectile dysfunction.
In men, opioids can also cause hypogonadism, which is a condition where the body doesn't produce enough sex hormones. This can lead to a decrease in sperm count and motility, as well as erectile dysfunction.
Additionally, opioid use can lead to weight gain, hyperglycaemia and worsening diabetes, which can further impact fertility.
Overall, opioid use can have a significant impact on fertility and should be considered when trying to conceive.
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Cocaine and ecstasy use can lead to permanent reproductive problems for people of all genders
Cocaine and ecstasy are both considered recreational drugs, and their long-term use can lead to permanent reproductive problems for people of all genders.
Cocaine is a psychoactive drug that can have a significant impact on male fertility. Studies have shown that cocaine use can lead to a decrease in sperm concentration, motility, and morphology. In one study, male rats exposed to cocaine had lower pregnancy rates and smaller litter sizes. Cocaine can also cause testicular shrinkage and impair spermatogenesis, the process by which sperm is produced.
Ecstasy, also known as MDMA, has been found to have negative effects on both male and female fertility. In males, ecstasy use can lead to a decrease in testosterone levels and sperm quality. In females, ecstasy can cause hormonal changes that affect ovulation and reduce the chance of pregnancy.
The use of cocaine and ecstasy can have serious consequences on reproductive health, and it is important to seek medical advice if you are trying to conceive and have a history of drug use.
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Frequently asked questions
Drugs and pollutants can have a detrimental impact on fertility, reducing the chances of conceiving and having a healthy baby. This applies to both men and women.
Drug misuse can directly affect fertility by acting on the body systems responsible for reproduction. It can also have an indirect effect due to how drug use and addiction can impact health and lifestyle. In men, drug use can affect testosterone levels, sperm production, erectile function, and sex drive. In women, it can disrupt hormone production, the menstrual cycle, and ovulation.
Environmental pollution can impair fertility in all mammalian species, with more severe consequences observed in females due to the fixed number of germ cells in the ovaries. Pollutants can affect hormonal homeostasis and the reproductive system, leading to reduced fertility and an increased risk of congenital anomalies.
Specific drugs that can negatively impact fertility include:
- Cannabis
- Cocaine
- Heroin
- Ecstasy
- Anabolic steroids
- Tobacco
- Alcohol
- Opioids
- Prescription medications (e.g., thyroid medications, mental health drugs)
Specific pollutants that can affect fertility include:
- Heavy metals (e.g., lead, cadmium, mercury)
- Air pollutants (e.g., particulate matter, nitrogen dioxide, sulfur dioxide, ozone)
- Endocrine disruptors (e.g., phthalates, bisphenol A)